Hiệu quả áp dụng gói hồi sức 1 giờ trong điều trị bệnh nhân sốc nhiễm khuẩn tại Bệnh viện Bệnh Nhiệt đới Trung ương

Septic shock is a multi-organ failure, hypotension leading to tissue hypoperfusion with a high mortality rate if not treated promptly. Objectives: To analyze the effectiveness of the application of a hour -1 bundle in patients with septic shock. Methods: Prospective analysis, comparing treatment results on 2 groups of septic shock patients with and without the hour - 1 bundle. Results: Septic shock is a serious disease, the mortality rate in our study is still high (60.2%), the main entrance is from the gastrointestinal tract (36.7%), male accounts for mainly (71.4%). The rate of complete application of the hour - 1 bundle of initial septic shock resuscitation on patients was high at 77.6%, the most common measure was blood culture before antibiotics (100.0%), low especially fluid resuscitation of at least 30 ml/kg in the first hour (68.0%). The mortality rate at hospital discharge was 60.2%, of which the mortality rate in the group that completed the 1-hour package was 54.0%, which was 81.8% lower than that in the group that did not complete the hour - 1 bundle. Conclusion: 1-hour early resuscitation package is effective in reducing mortality in patients with septic shock.