Khảo sát nồng độ acid uric máu lúc nhập viện và mối liên quan với một số đặc điểm lâm sàng, cận lâm sàng ở bệnh nhân sốc nhiễm khuẩn

To investigate the rate of hyperuricemia and the relationship between blood uric acid levels and some clinical and paraclinical characteristics in patients with septic shock. Subjects and methods: 44 patients were diagnosed with septic shock according to Sepsis-3. Uric acid test performed at the time of admission, hyperuricemia is defined as blood uric acid concentration in men > 420 μmol/l and in women > 360 μmol/l. Results: 37/44 patients had hyperuricemia, accounting for 84.1%. SOFA score, blood urea concentration, blood creatinine concentration and blood lactate concentration in the group of patients with hyperuricemia were statistically significantly higher than the group of patients without hyperuricemia. There is a moderate positive correlation between blood uric acid levels and blood urea and creatinine levels, the correlation coefficients are 0.496 and 0.507, respectively, p<0.05. Conclusion: Hyperuricemia accounts for a fairly high rate, blood uric acid levels are positively correlated with blood urea and creatinine in patients with septic shock.