A retrospective study was carried out from April 1st 2009 to July 1st 2010 at Khanh Hoa Hospital to identify invasive pathogenic bacteria from fecal materials of patients admitted to Department of Infectious Diseases and Dept. of Pediatrics with the diagnosis of dysenteric syndrome. After being identified, these isolates were cultured to determine their susceptibility to antibiotics. From 84 isolates, Shigella sonnei took the highest percentage of 71.43 percent, and followed by Shigella fIexneri with 14.29 percent, and other entero- pathogenic agents such as E. coli with 5.95 percent, Salmonella 5.95 percent, Yersinia enterocolitica 2.38 percent. Shigella dysenteriae and Shigella boydii were not detected. Concerning antibiotic susceptibility, the resistance of Shigella sonnei and Shigella flexneri to Ampicillin, Bactrim and Nalixidic acid varied from 83 to 100 percent. In addition, 45.00 percent of Shigella sonnei secretes enzyme ESBL. This study confirms that 3 antibiotics Ampiclin, Bactrim and Nalidixic have lost their effectiveness in treating Shigellosis. Besides, Shigella sonnei resitant to Betalactam is 45.00 percent.
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