Nghiên cứu đánh giá nồng độ AFP, AFP-L3 ở bệnh nhân ung thư biểu mô tế bào gan có HBV dương tính

The study on 65 patients with confirmed diagnosis of carcinoma, hepatocellular including 44 male and 21 female. The results showed that the concentration of AFP, AFP-L3 and AFP-L3/AFP rate in the study group, respectively: AFP 4111.64 + or - 4553.14 (ng/ml) in the group of HBsAg (+) and 2193,34 + or - 8076,47 (ng/ml) in the group of HBsAg( -); meanwhile, the concentration of AFP-L3 2643.46 + or - 12343.60 (ng/ml) in the group of HBsAg(+) and 414.60 + or - 1571.15 (ng/ml) in the group of HBsAg(-); whereas, the ratio of AFP-L3/AFP was statistically significant difference in the 2 groups with HBsAg (+)/(-). Furthermore, evaluating CT image shows the relevant statistical significance with p 0.01 between concentrations of AFP, AFP-L3 with tumor number, tumor size, and degree of proliferation as the level of drug absorption.