Nghiên cứu hoạt động transaminase, rối loạn glucose máu, lipid máu ở bệnh nhân gan nhiễm mỡ không do rượu

Study on finding new biomarkers for early diagnosis of hepatocellular carcinoma (HCC) are trend currently. Using sequencing assay we analyzed HBX gene of hepatitis B virus (HBV) in 190 patients infected with HBV. HBX mutation is increasingly from asymptomatic chronic HBV carriers (ASY) to chronic B hepatitis (CHB) and highest in HCC group. Point mutation rate at C1653T in ASY, CHB and HCC is 2, 6 and 57.7 percent; at T1753C is 2, 8, and 25.5 percent; atA1762T is 26.52, and 82.2 percent; at G1764A is 28.56, and 86.6 percent and at C1766T is 2, 6 and 22.2 percent, respectively. These mutations are associated with the risk of developing NCC: C1653T' p 0. 0001, OR