Nghiên cứu một số chỉ số hóa sinh chức năng gan ở bệnh nhân viêm gan virut B mạn tính

Blood biochemical tests play an important role in the diagnosis and treatment monitoring in clinical practice. The aim of research is to measure some liver function test in hepatitis patients caused by hepatitis B virus infection. Subjects: Proceed on 200 peoples, including 100 patients with hepatitis B virus infection and 100 normal healthy peoples. Methodology: Conducted clinical examination, blood testing for HBsAg and determined AST, ALT, GGT activity, haptoglobine, total and direct bilirubine levels. Results: The patient group with the activity of AST, ALT, GGT increased from 2-5 times in comparison with the one's normal value, respectively accounting for 42, 20 and 30 percent while these percentages in the group with the activity increased 5 times were 18, 4 and 44 percent. The group having total and direct bilirubine increased 5 times in comparison with normal values were 4 percent in the group of patients while these percentages in the group with an increase from 2-5 times were 36 percent and 34 percent. Haptoglobine level in the HBV hepatitis patient group was 0.34 +/- 0.34 g/l, this value decreased significantly compared to the control group (0.970.57 g/l) and lower than the normal value (0.13 - 1.63 g/l). Conclusion: In patients with HBV hepatitis, the haptoglobine level decreased significantly compared with the control group (p 0,05). There is a change of liver function test in hepatitis B patients.