Tìm hiểu mối liên quan giữa nồng độ kháng thể H.Pylori với biểu hiện lâm sàng, nội soi và mô bệnh học ở bệnh nhân viêm, loét dạ dày tá tràng do H.Pylori

Helicobacter pylori is associated with chronic gastritis and peptic ulcer in adults and in children. The purpose of the present study was to analyze the association the relationship between H. pylori antibody concentration in blood with the clinical signs, endoscopy findings and histology in gastritis children. Materials and methods: In a prospective study, 238 patients were diagnosed gastritis and peptic ulcer based on gastroscopy, RUT, H. pylori culture and IgG. Results: No significant diference in clinical manifestations between group of IgG levels or = 1 when compared with IgG levels 1. The were significant differences in rate of mucosal edema, peptic ulcer between two group of IgG levels or = 1 and 1. The rates of mucosa edema, gland degeneration, polymorphonuclear proliferation, severe inflammatory lesions and H. pylori counts in group IgG or = 1 were significantly higher when compared to IgG levels 1 (p 0.05). Conclusion: No correlation between the H. pylori IgG level and the clinical signs, but high level of H. pylori IgG was associated with increased mucosal damage and changes in gastric mucosa.