Tóm tắt khuyến cáo của EASL 2011 trong điều trị viêm gan siêu vi C

The ultimate goals of antiviral therapy are to eliminate HCV, improve or normalize the liver tests and histology, prevent progression to cirrhosis and liver cancer. Only a sustained virologic response provides the possibility oj achieving all of the ultimate goals, since most patients who have an SVR will remain in remission indefinitely. The optimal treatment is now still a combined treatment with pegylated inter feron and ribavirin. The duration of therapy depends on the genotype of the HCV. The recommended duration of treatment for HCV genotype 2 and 3 is 24 weeks and for genotype 1 is 48 weeks. Two protease inhibitors : boceprevir and telaprevir are awaiting approval in the United States. The triple therapy: pegylated interferon, ribavirin and protease inhibitor may increase SVR and thus, increase our ability to cure hepatitis C genotype 1.